Seminars on novel therapeutic targets in oncology

2nd year - 2 credits

Learning Objectives

At the end of the course, PhD students will have acquired the main notions relating to the diagnostic and treatment techniques used in the treatment of sarcomas, as well as a vision of the open problems and challenges that the treatment of rare tumors poses in the surgical, diagnostic, oncological and research fields.

This course focuses on acquiring key concepts such as bypass pathways, feedback loops and their interaction with steroid hormones.  It will cover the field of cell signalling and will help the students to develop a deep understanding of biological complexities.

Module 1 - Professor Katia Scotlandi

Course Timetable

28th January 2025, 14:00 - 18:00
29th January 2025, 14:00 - 18:00

Course Contents

-Prof. Davide Maria Donati: Sarcomas of the bone: clinical aspects and treatment techniques
-Dr. Toni Ibrahim: The role of medical oncology: from taking care to personalized medicine
-Dr. Marco Gambarotti: Histo-pathological aspects and molecular diagnostics
-Prof. Katia Scotlandi: Biological aspects and the role of genetics in the design of new therapeutic treatments in sarcomas

Teaching Modality

Online via Teams

Module 2 - Professor Mattia Lauriola and Professor Kenneth Marcu

Course Timetable

201 - AULETTA MULTIMEDIALE (Access from via Belmeloro 8)
10th February 2025, 14:30 - 16:30 (Professor Kenneth Marcu)
11th February 2025, 14:30 - 16:30 (Professor Kenneth Marcu)

13th February 2025, 14:30 - 16:30 (Professor Mattia Lauriola)

201 - AULA A. RUFFINI - Accesso da Via Belmeloro 8/2
17th February 2025, 14:30 - 16:30 (Professor Mattia Lauriola)

Course Contents


10th February: Transcription in vivo is mediated by long distance acting enhancers and insulators
11th February: Interplay/crosstalk of Rb/E2F, c-Myc, p53 and NF-kB dependent transcriptional control in normal vs. cancerous/malignant mammalian cell physiology
13th February: Mechanisms of resistance to EGFR inhibitors
17th February: Molecular Alterations in the ERBB family and the Rational for the Combinatorial Therapy


Teaching Modality

Online via Teams and In presence